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Nervous System Anatomy & Physiology

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  • Organization of the nervous system

    The nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS includes the brain and spinal cord, while the PNS includes all neural tissue outside the CNS.

  • Parts of a neuron

    A neuron consists of the cell body (soma), dendrites (receive signals), and an axon (transmits signals away from the cell body).

  • Function of dendrites

    Dendrites receive incoming signals from other neurons and transmit them toward the cell body.

  • Function of the axon

    The axon conducts electrical impulses away from the cell body to other neurons or effector cells.

  • Parts of a synapse

    A synapse includes the presynaptic terminal (axon terminal), synaptic cleft (gap), and postsynaptic membrane (on dendrite or cell body).

  • Function of the presynaptic terminal

    The presynaptic terminal releases neurotransmitters into the synaptic cleft to transmit signals.

  • Function of the synaptic cleft

    The synaptic cleft is the space where neurotransmitters diffuse to reach the postsynaptic membrane.

  • Function of the postsynaptic membrane

    The postsynaptic membrane contains receptors that bind neurotransmitters to propagate the signal.

  • Types of glial cells in the CNS

    Major CNS glial cells include astrocytes, oligodendrocytes, microglia, and ependymal cells.

  • Functions of astrocytes

    Astrocytes support neurons, maintain the blood-brain barrier, regulate ion balance, and repair tissue.

  • Functions of oligodendrocytes

    Oligodendrocytes produce myelin sheaths that insulate CNS axons to speed conduction.

  • Functions of microglia

    Microglia act as immune cells in the CNS, removing debris and pathogens.

  • Functions of ependymal cells

    Ependymal cells line ventricles and produce cerebrospinal fluid (CSF).

  • Definition of gray matter

    Gray matter consists mainly of neuronal cell bodies, dendrites, and unmyelinated axons.

  • Definition of white matter

    White matter is composed primarily of myelinated axons forming tracts for communication.

  • Definition of tracts in the CNS

    Tracts are bundles of myelinated axons in the CNS that connect different regions.

  • Definition of nuclei in the CNS

    Nuclei are clusters of neuron cell bodies within the CNS with specific functions.

  • Formation of cerebrospinal fluid (CSF)

    CSF is produced by the choroid plexus in the brain ventricles through filtration and secretion.

  • Distribution of cerebrospinal fluid

    CSF circulates through the ventricles, central canal of the spinal cord, and subarachnoid space around the brain and spinal cord.

  • Functions of cerebrospinal fluid

    CSF cushions the brain, removes waste, and provides a stable chemical environment.

  • Structure of the blood-brain barrier

    The blood-brain barrier consists of endothelial cells with tight junctions, supported by astrocyte end-feet.

  • Functions of the blood-brain barrier

    It protects the brain by regulating substance passage from blood to neural tissue, maintaining homeostasis.

  • Major subdivisions of the cerebrum

    The cerebrum includes the frontal, parietal, temporal, and occipital lobes, each with distinct functions.

  • Major subdivisions of the cerebellum

    The cerebellum has two hemispheres and a central vermis, coordinating movement and balance.

  • Major subdivisions of the diencephalon

    The diencephalon includes the thalamus, hypothalamus, and epithalamus, involved in sensory relay and autonomic control.

  • Major subdivisions of the brain stem

    The brain stem consists of the midbrain, pons, and medulla oblongata, controlling vital functions.

  • Anatomical relationships of brain subdivisions

    The brain stem connects the spinal cord to the cerebrum and cerebellum; the diencephalon lies above the brain stem; the cerebrum is the largest, most superior part.