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Respiratory System Anatomy & Physiology

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  • Location and function of the nose

    The nose is the main external opening for the respiratory system. It filters, warms, and moistens air and houses olfactory receptors.

  • Function of paranasal sinuses

    Paranasal sinuses lighten the skull, produce mucus, and help warm and moisten inhaled air.

  • Role of the pharynx in respiration

    The pharynx serves as a passageway for air and food; it connects the nasal cavity to the larynx and esophagus.

  • Protective mechanisms of the respiratory system

    Includes mucus production, cilia movement, coughing, sneezing, and reflexes to trap and expel particles.

  • Difference between conducting and respiratory zones

    The conducting zone transports air; the respiratory zone is where gas exchange occurs (alveoli).

  • Structure and function of the larynx

    The larynx contains vocal cords, routes air and food, and protects the airway during swallowing.

  • Role of the trachea in respiration

    The trachea is a rigid tube that conducts air to the bronchi and is lined with ciliated mucosa to trap debris.

  • Function of the bronchi

    Bronchi branch from the trachea to deliver air to each lung and further divide into bronchioles.

  • Composition of the respiratory membrane

    The respiratory membrane consists of alveolar and capillary walls and their fused basement membranes, allowing efficient gas exchange.

  • Order of respiratory passageways to alveoli

    Nose → pharynx → larynx → trachea → bronchi → bronchioles → alveolar ducts → alveoli.

  • Gross structure of the lungs and pleurae

    Lungs are paired organs with lobes; the pleurae are serous membranes that reduce friction and create a pressure gradient.

  • Importance of the intrapleural space vacuum

    The partial vacuum in the intrapleural space keeps lungs inflated by preventing lung collapse.

  • Boyle’s law in breathing

    Boyle’s law: Pressure and volume are inversely related; lung volume changes cause pressure changes that drive air flow.

  • Role of respiratory muscles in ventilation

    Diaphragm and intercostal muscles change thoracic volume, enabling inspiration and expiration.

  • Physical factors influencing pulmonary ventilation

    Include airway resistance, lung compliance, and surface tension of alveolar fluid.

  • Definition of dead space

    Dead space is the volume of air in conducting passages that does not participate in gas exchange.

  • Lung volumes and capacities

    Includes tidal volume, inspiratory reserve, expiratory reserve, residual volume, and combinations like vital capacity.

  • Dalton’s law of partial pressures

    In a gas mixture, each gas exerts pressure proportional to its concentration.

  • Henry’s law in gas exchange

    The amount of gas dissolved in a liquid is proportional to its partial pressure and solubility.

  • Differences between atmospheric and alveolar air

    Alveolar air has higher CO2 and water vapor, and lower O2 due to gas exchange and humidification.

  • Oxygen transport in blood

    Oxygen is mostly bound to hemoglobin in red blood cells; a small amount is dissolved in plasma.

  • Factors affecting oxygen loading/unloading from hemoglobin

    PO2, temperature, pH, BPG, and PCO2 influence hemoglobin’s oxygen affinity.

  • Carbon dioxide transport in blood

    CO2 is transported as bicarbonate ions, bound to hemoglobin, and dissolved in plasma.