Tissue Injuries and Repair in Anatomy & Physiology
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Inflammation (inflammatory response) and regeneration to restore normal function.
Trauma (physical injury) and infection (presence of pathogens).
Prostaglandins, proteins, and potassium ions.
Damaged connective tissue activates mast cells which contribute to inflammation.
Redness, swelling, heat, and pain.
Lysosomes release enzymes that destroy injured cells and attack surrounding tissues.
Tissue destruction that begins several hours after injury.
Necrotic tissues and cellular debris (pus) accumulate.
Pus trapped in an enclosed area within tissue.
Epithelia, connective tissues (except cartilage), and smooth muscle regenerate well.
Skeletal muscle, cardiac muscle, and nervous tissues regenerate poorly or not at all.
They are replaced by fibrous tissue through fibrosis.
Collagen fibers to stabilize the injury site.
A dense, collagenous framework produced by fibroblasts during tissue repair.
It is remodeled and normal tissue conditions are restored.