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Cellular Respiration and ATP Production

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  • What is cellular respiration?

    Cellular respiration is a catabolic pathway that converts organic molecules like glucose into usable energy in the form of ATP.

  • What is the general chemical equation for aerobic cellular respiration?

    \(\mathrm{C_6H_{12}O_6 + 6O_2 \rightarrow 6CO_2 + 6H_2O + ATP + heat}\)

  • What are the four main stages of cellular respiration?

    Glycolysis, Intermediate Step (Oxidation of Pyruvate), Citric Acid Cycle (Kreb's Cycle), Electron Transport Chain (Oxidative Phosphorylation).

  • Where does glycolysis occur and what are its inputs and outputs?

    Occurs in the cytoplasm; inputs: 1 glucose, 2 ATP, 2 NAD+; outputs: 2 pyruvate, 2 ATP, 2 NADH, 2 H2O.

  • What happens during the oxidation of pyruvate?

    Pyruvate is converted into Acetyl-CoA in the mitochondrial matrix, producing 1 NADH and 1 CO2 per pyruvate.

  • What is the role of the Citric Acid Cycle (Kreb's Cycle)?

    It oxidizes Acetyl-CoA to produce 3 NADH, 1 FADH2, 1 ATP, and 2 CO2 per cycle in the mitochondrial matrix.

  • Where does the Electron Transport Chain occur and what is its function?

    Occurs in the inner mitochondrial membrane (cristae); it transfers electrons from NADH and FADH2 to oxygen, pumping H+ ions to create a gradient.

  • What is chemiosmosis in cellular respiration?

    Exergonic diffusion of H+ ions through ATP synthase back into the matrix, driving ATP production.

  • How does ATP synthase produce ATP?

    It uses kinetic energy from H+ ions moving down their gradient to bind ADP and inorganic phosphate, forming ATP.

  • What is substrate-level phosphorylation?

    Direct enzymatic transfer of a phosphate group to ADP to form ATP during glycolysis and the Citric Acid Cycle.

  • What is the difference between aerobic and anaerobic respiration?

    Aerobic uses oxygen as the final electron acceptor; anaerobic does not and may use fermentation instead.

  • What are the products of lactic acid fermentation?

    2 ATP, 2 lactate molecules, and heat from glucose breakdown without oxygen.

  • What are the products of ethanol fermentation?

    2 ATP, 2 ethanol molecules, 2 CO2, and heat from glucose breakdown without oxygen.

  • What is the role of NAD+ in cellular respiration?

    NAD+ acts as an electron carrier, accepting electrons during oxidation reactions to form NADH.

  • What is a redox reaction?

    A chemical reaction involving the transfer of electrons where one molecule is oxidized and another is reduced.

  • How many ATP molecules are typically produced per glucose molecule during aerobic respiration?

    Approximately 36 to 38 ATP molecules are produced per glucose molecule.

  • What is the proton-motive force?

    The electrochemical gradient of H+ ions across the mitochondrial membrane used to drive ATP synthesis.

  • What happens to electrons at the end of the Electron Transport Chain?

    Electrons combine with oxygen and H+ ions to form water.

  • What is the function of the mitochondrial cristae?

    They increase surface area for the Electron Transport Chain and ATP synthesis.

  • What is the net ATP gain from glycolysis alone?

    2 ATP molecules are produced per glucose molecule during glycolysis.