Prokaryotic cells lack a membrane-bound nucleus and have DNA in a nucleoid region; eukaryotic cells have a membrane-bound nucleus containing DNA.
Cell Membrane Composition
The cell membrane is composed of a phospholipid bilayer with hydrophilic heads and hydrophobic tails, embedded with proteins, glycolipids, glycoproteins, and cholesterol.
Surface-to-Volume Ratio Importance
Cells have a high surface-to-volume ratio to maximize exchange of materials across the membrane for efficient metabolism.
Phospholipid Structure
Phospholipids have a hydrophilic phosphate head and two hydrophobic fatty acid tails, forming bilayers in aqueous environments.
Amino Acid R Groups
Amino acid R groups determine polarity: hydrophobic (e.g., leucine), hydrophilic (e.g., serine, aspartic acid).
Fluid Mosaic Model
Describes the cell membrane as a dynamic structure with proteins moving laterally within the phospholipid bilayer.
Nucleus Function
The nucleus stores genetic information (DNA) and controls protein synthesis via transcription to RNA.
Ribosome Role
Ribosomes synthesize proteins by translating mRNA; they are not membrane-bound.
Endoplasmic Reticulum (ER) Types
Rough ER has ribosomes and synthesizes proteins; Smooth ER synthesizes lipids, detoxifies drugs, and stores calcium.
Golgi Apparatus Function
Modifies, sorts, and ships proteins received from the ER; has a cis (receiving) and trans (shipping) face.
Lysosome Function
Membrane-bound sac containing digestive enzymes that break down macromolecules and damaged organelles.
Vacuole Types
Large vesicles for food storage, contractile function, or storage of organic molecules.
Mitochondria Role
Site of catabolic metabolism; breaks down molecules to generate ATP.
Chloroplast Role
Site of anabolic metabolism; converts light energy into chemical energy (sugar) via photosynthesis.
Peroxisome Function
Contains enzymes that detoxify hydrogen peroxide and metabolize long-chain fatty acids; not part of the endomembrane system.
Cytoskeleton Components
Includes microtubules, microfilaments, and intermediate filaments providing structure, transport, and motility.
Microtubules
Thick, hollow tubes made of tubulin; provide tracks for organelle movement and form cilia and flagella.
Microfilaments
Thin fibers made of actin; support cell shape and enable muscle contraction and amoeboid movement.
Intermediate Filaments
Fibrous proteins forming permanent cables that reinforce cell shape and anchor organelles.
Cell Junctions in Animals
Tight junctions seal cells, anchoring junctions connect cells via intermediate filaments, gap junctions allow molecule passage.
Plant Cell Wall Composition
Made of cellulose fibers embedded in polysaccharides and proteins; provides protection and structure.
Plasmodesmata
Channels between plant cells that allow water, nutrients, and chemical signals to pass.
Central Dogma of Molecular Biology
DNA is transcribed into RNA, which is translated into protein.
Endomembrane System
Network of membranes including ER, Golgi, lysosomes, and vesicles that regulate protein traffic and metabolism.