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General Biology Core Concepts

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  • Protons, Neutrons, Electrons

    Protons have a positive charge and are in the nucleus.

    Neutrons have no charge and are in the nucleus.

    Electrons have a negative charge and orbit outside the nucleus.

  • Atomic Number vs Mass Number

    Atomic number = number of protons.

    Mass number = protons + neutrons.

  • Ions: Cations and Anions

    Cations are positive ions formed by losing electrons.

    Anions are negative ions formed by gaining electrons.

  • Types of Chemical Bonds

    Covalent bonds share electrons;

    ionic bonds transfer electrons;

    hydrogen bonds are weak attractions important in water and DNA.

  • Water Polarity and Properties

    Water is polar with slight negative (oxygen) and positive (hydrogen) sides, leading to cohesion, adhesion, surface tension, and ice being less dense than liquid water.

  • Carbohydrates Functions and Examples

    Provide quick energy and structure.

    Examples: glucose (monosaccharide), starch (plant storage), glycogen (animal storage), cellulose (plant cell walls).

  • Lipids Characteristics

    Function in long-term energy storage, cell membranes, and hormones. They are hydrophobic. Include saturated (no double bonds) and unsaturated fats (double bonds).

  • Phospholipids in Cell Membranes

    Have hydrophilic heads and hydrophobic tails, forming bilayers that control what enters and leaves cells.

  • Proteins and Peptide Bonds

    Made of amino acids linked by peptide bonds. Functions include enzymes, structure, transport, and signaling.

  • Nucleic Acids and Base Pairing

    DNA and RNA made of nucleotides (phosphate, sugar, base). DNA pairs: A-T, C-G. RNA pairs: A-U, C-G.

  • Prokaryote vs Eukaryote Cells

    Prokaryotes: no nucleus, smaller, circular DNA, no membrane organelles. Eukaryotes: nucleus, larger, linear DNA, membrane organelles.

  • Key Organelles and Functions

    Nucleus: stores DNA.

    Ribosomes: make proteins.

    Rough ER: protein processing.

    Smooth ER: lipid synthesis.

    Golgi: packages proteins.

    Mitochondria: makes ATP.

  • Endosymbiotic Theory Evidence

    Mitochondria and chloroplasts have circular DNA, 70S ribosomes, binary fission, and double membranes, suggesting they were once bacteria.

  • Scientific Method Variables

    Independent variable: what is changed.

    Dependent variable: what is measured. Hypothesis: testable prediction.

    Theory: well-supported explanation.

  • ATP Role and Cycle

    ATP is the cell's immediate energy currency. ATP breaks down to ADP + phosphate + energy; energy from food rebuilds ATP.

  • Enzymes and Activation Energy

    Enzymes are proteins that speed up reactions by lowering activation energy without being consumed.

  • Passive vs Active Transport

    Passive transport: no energy, moves substances high → low concentration.

    Active transport: uses ATP, moves substances low → high concentration.

  • Cell Membrane Structure and Function

    Made of a phospholipid bilayer with hydrophilic heads and hydrophobic tails.

    Controls what enters and leaves the cell, maintaining homeostasis.

  • Plant vs Animal Cell Differences

    Plant cells have cell walls, chloroplasts, and large central vacuoles. Animal cells lack these but have mitochondria and a nucleus.

  • Microscopy Types

    Light microscope: living cells, color, lower resolution.

    SEM: surface details, 3D.

    TEM: internal structures, thin slices.

  • Characteristics of Life

    Living things are made of cells, use energy, grow, respond to environment, maintain homeostasis, reproduce, have DNA, and evolve.

  • Levels of Biological Organization

    Atom → Molecule → Organelle → Cell → Tissue → Organ → Organ System → Organism → Population → Community → Ecosystem → Biosphere.

  • Energy Transformations in Biology

    Energy changes form, e.g., chemical energy in food → ATP → movement; some energy lost as heat.

  • Hydrogen Bond Importance

    Hydrogen bonds occur between F, O, N atoms and are crucial for water's properties and DNA structure.

  • Enzyme Inhibitors

    Substances that reduce enzyme activity by preventing substrate binding or altering enzyme shape.