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General Biology: Organic Chemistry and Macromolecules

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  • Difference between inorganic and organic compounds

    Organic compounds contain carbon and hydrogen, have covalent bonds, and are associated with living organisms. Inorganic compounds usually have ionic bonds, dissociate in water releasing ions, and are associated with nonliving matter.

  • Why is carbon important in organic molecules?

    Carbon has 4 valence electrons allowing it to form 4 covalent bonds, creating diverse molecules with tetrahedral shapes and complex skeletons.

  • What are hydrocarbons?

    Organic molecules consisting only of carbon and hydrogen atoms, forming chains or rings, and can release large amounts of energy when broken down.

  • Four ways carbon skeletons can vary

    Length, branching, double bond position, and presence of rings.

  • What are isomers?

    Compounds with the same molecular formula but different structures and properties.

  • Types of isomers

    Structural isomers: different covalent arrangements.
    Cis-trans isomers: differ in spatial arrangement around double bonds.
    Enantiomers: mirror images of each other.

  • What are functional groups?

    Specific groups of atoms attached to carbon skeletons that give organic molecules distinct chemical properties.

  • How do functional groups affect organic molecules?

    They change polarity and solubility, making molecules hydrophilic or hydrophobic, and influence chemical reactivity.

  • What are macromolecules?

    Large organic molecules made up of smaller units called monomers linked into polymers.

  • Define monomer and polymer

    Monomer: small repeating unit.
    Polymer: chain of monomers linked together.

  • What is a dehydration reaction?

    A chemical reaction that removes a water molecule to form a covalent bond between monomers, synthesizing polymers and requiring energy.

  • What is hydrolysis?

    A reaction that adds water to break covalent bonds between monomers, degrading polymers and releasing energy.

  • Functions of carbohydrates

    Serve as energy sources, energy storage, and structural components in cells.

  • Difference between monosaccharides, disaccharides, and polysaccharides

    Monosaccharides: single sugar molecules.
    Disaccharides: two monosaccharides joined.
    Polysaccharides: long chains of monosaccharides.

  • Examples of storage polysaccharides

    Starch: plant storage polymer of glucose.
    Glycogen: animal storage polymer of glucose.

  • Structural polysaccharides

    Cellulose: plant cell wall component.
    Chitin: exoskeleton of arthropods and fungal cell walls.

  • Are lipids polar or non-polar?

    Lipids are non-polar and hydrophobic, meaning they do not mix well with water.

  • Structure and function of triglycerides

    Composed of glycerol and three fatty acids; function as long-term energy storage and insulation.

  • Difference between saturated and unsaturated fats

    Saturated fats: no double bonds, solid at room temperature.
    Unsaturated fats: one or more double bonds, liquid at room temperature.

  • What is hydrogenation and trans fats?

    Hydrogenation adds hydrogen to unsaturated fats, making them saturated and creating trans fats, which are unhealthy.

  • Why are phospholipids amphipathic?

    They have a hydrophilic (polar) head and two hydrophobic (nonpolar) fatty acid tails, allowing them to form bilayers in water.

  • General structure of steroids

    Consist of four fused carbon rings; cholesterol is the precursor molecule for other steroids.

  • What are proteins and their monomers?

    Proteins are polymers made of amino acid monomers linked by peptide bonds.

  • Functions of proteins

    Include enzymatic catalysis, structural support, transport, communication, movement, and defense.

  • Four levels of protein structure

    Primary: amino acid sequence.
    Secondary: α helices and β sheets formed by hydrogen bonds.
    Tertiary: 3D folding from side chain interactions.
    Quaternary: multiple polypeptide chains assembled.

  • What causes protein denaturation?

    Changes in pH, salt concentration, temperature, or environment can unravel proteins, making them biologically inactive.

  • What are nucleic acids?

    Macromolecules that store and transmit genetic information; polymers of nucleotides.

  • Difference between DNA and RNA

    DNA is double-stranded with deoxyribose sugar and stores genetic info; RNA is single-stranded with ribose sugar and helps synthesize proteins.

  • Purines vs Pyrimidines

    Purines: adenine and guanine with two rings.
    Pyrimidines: cytosine, thymine (DNA), and uracil (RNA) with one ring.