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Membrane Transport and Cell Signaling

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  • What are the major components of biological membranes?

    Biological membranes are composed mainly of phospholipid bilayers with embedded proteins and cholesterol.
  • What does the Fluid Mosaic Model describe?

    The Fluid Mosaic Model describes membranes as fluid structures with a mosaic of membrane-embedded proteins that move laterally.
  • What are the two main types of membrane proteins?

    1) Integral membrane proteins span the bilayer. 2) Peripheral membrane proteins are attached to the membrane surface.
  • Name some functions of membrane proteins.

    Membrane proteins function in transport, signal transduction, cell recognition, enzymatic activity, and cytoskeleton anchoring.
  • Define concentration gradient.

    A concentration gradient is the difference in concentration of a substance between two areas.
  • What is diffusion?

    Diffusion is the movement of molecules from an area of high concentration to low concentration without energy input.
  • What does selectively permeable mean in membranes?

    Selectively permeable membranes allow some substances to cross while blocking others based on size, charge, or polarity.
  • Which molecules freely diffuse across membranes without protein facilitation?

    Small, nonpolar molecules like O2 and CO2 freely diffuse across membranes.
  • What are the two general types of molecular transport across membranes?

    1) Passive transport (no energy, down gradient). 2) Active transport (energy required, against gradient).
  • What is the difference between passive and active transport?

    Passive transport moves substances down their concentration gradient without energy; active transport moves substances against their gradient using energy.
  • What are uniporters, symporters, and antiporters?

    Uniporters transport one molecule in one direction; symporters transport two molecules in the same direction; antiporters transport two molecules in opposite directions.
  • Define osmosis.

    Osmosis is the passive diffusion of water across a semi-permeable membrane from low to high solute concentration.
  • What is the difference between hypotonic, isotonic, and hypertonic solutions?

    Hypotonic: lower solute outside, water enters cell. Isotonic: equal solute, no net water movement. Hypertonic: higher solute outside, water leaves cell.
  • What happens to cells in hypotonic environments?

    Cells swell as water enters; plant cells become turgid, animal cells may lyse (burst).
  • What are simple diffusion and facilitated diffusion?

    Simple diffusion is direct movement of small uncharged molecules; facilitated diffusion uses transport proteins for charged or large molecules without energy.
  • What types of transport proteins assist facilitated diffusion?

    Porins/channels form pores; aquaporins transport water; carriers undergo conformational changes to move molecules.
  • What is primary active transport?

    Primary active transport uses ATP hydrolysis to move molecules against their concentration gradient.
  • Describe the sodium-potassium pump.

    It is a primary active antiporter that moves 3 Na+ ions out and 2 K+ ions into the cell using ATP.
  • What is secondary active transport?

    Secondary active transport uses the concentration gradient established by primary active transport to move other molecules.
  • What are endocytosis and exocytosis?

    Endocytosis brings large molecules into the cell via vesicles; exocytosis expels molecules out of the cell via vesicle fusion.
  • Name the three types of endocytosis.

    Phagocytosis (cell eating), pinocytosis (cell drinking), and receptor-mediated endocytosis (selective uptake).