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Ch. 9 - The Molecular Biology of Translation
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
9장, 문제 9

What is the role of codons UAA, UGA, and UAG in translation? What events occur when one of these codons appears at the A site of the ribosome?

검증된 단계별 안내
1
Identify the role of codons UAA, UGA, and UAG in the genetic code.
Understand that these codons are known as stop codons.
Explain that stop codons signal the termination of protein synthesis during translation.
Describe the process that occurs when a stop codon appears at the A site of the ribosome.
Discuss how release factors bind to the stop codon, leading to the release of the polypeptide chain from the ribosome.

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주요 개념

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Codons and Their Function

Codons are sequences of three nucleotides in mRNA that correspond to specific amino acids or signal the termination of protein synthesis. The codons UAA, UGA, and UAG are known as stop codons, which do not code for any amino acid but instead signal the ribosome to halt translation.
추천 영상:
가이드 코스
08:26
Functional Genomics

Translation Process

Translation is the process by which ribosomes synthesize proteins by decoding mRNA. During translation, the ribosome moves along the mRNA, and tRNA molecules bring the appropriate amino acids to the growing polypeptide chain. The A site of the ribosome is where the incoming tRNA binds, and the presence of a stop codon here triggers the termination of translation.
추천 영상:
가이드 코스
08:39
mRNA Processing

Termination of Translation

When a stop codon (UAA, UGA, or UAG) appears at the A site of the ribosome, it is recognized by release factors instead of tRNA. These factors promote the release of the newly synthesized polypeptide chain from the ribosome, leading to the disassembly of the translation complex and the completion of protein synthesis.
추천 영상:
가이드 코스
01:55
Translation Termination