Rejection of a foreign skin graft is an example of:
a. Destruction of virus-infected cells
b. Tolerance
c. Antibody-mediated immunity
d. A secondary immune response
e. A cell-mediated immune response

검증된 단계별 안내

Understand the context of the problem: rejection of a foreign skin graft involves the immune system recognizing and attacking non-self tissue.

Recall that antibody-mediated immunity primarily involves B cells producing antibodies to neutralize pathogens, which is less relevant in graft rejection.

Consider that tolerance refers to the immune system's acceptance of antigens without attacking them, which is the opposite of graft rejection.

Recognize that destruction of virus-infected cells is typically carried out by cytotoxic T cells targeting infected host cells, but graft rejection involves a broader immune response to foreign tissue.

Identify that graft rejection is mainly driven by a cell-mediated immune response, where T cells recognize foreign antigens on the graft and initiate an immune attack, leading to rejection.

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주요 개념

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Cell-mediated immune response

This immune response involves T cells recognizing and destroying infected or foreign cells, such as transplanted tissue. It does not rely on antibodies but on direct cell-to-cell interactions, making it crucial for rejecting foreign grafts.

Graft rejection

Graft rejection occurs when the recipient's immune system identifies transplanted tissue as foreign and attacks it. This process primarily involves T cells recognizing non-self antigens on the graft, leading to inflammation and tissue destruction.

Tolerance

Tolerance is the immune system's ability to avoid attacking the body's own cells or harmless foreign substances. Failure of tolerance mechanisms can result in graft rejection, as the immune system treats the graft as a threat.

Rejection of a foreign skin graft is an example of:a. Destruction of virus-infected cellsb. Tolerancec. Antibody-mediated immunityd. A secondary immune responsee. A cell-mediated immune response