Ch. 14 - Biomedical Applications: Vaccines, Diagnostics, Therapeutics, and Molecular Method

Norman-McKay- Microbiology: Basic and Clinical Principles 2nd Edition

Norman-McKay2nd EditionMicrobiology: Basic and Clinical PrinciplesISBN: 9780137661619당신이 사용하는 게 아니라요?교과서 변경

Norman-McKay 2nd Edition

Ch. 14 - Biomedical Applications: Vaccines, Diagnostics, Therapeutics, and Molecular Method

문제 2

10장, 문제 2

Which of the following vaccines is most likely to be contraindicated for an immune compromised patient?
a. An mRNA vaccine
b. A whole inactivated vaccine
c. A toxoid vaccine
d. A conjugate vaccine
e. A live attenuated vaccine

검증된 단계별 안내

Step 1: Understand the types of vaccines listed and their general characteristics. An mRNA vaccine uses messenger RNA to instruct cells to produce an antigen, a whole inactivated vaccine contains killed pathogens, a toxoid vaccine contains inactivated toxins, a conjugate vaccine links polysaccharides to proteins to enhance immune response, and a live attenuated vaccine contains weakened but live pathogens.

Step 2: Recall that immune compromised patients have weakened immune systems, making them more vulnerable to infections and less able to handle live pathogens, even if attenuated.

Step 3: Identify which vaccine type contains live organisms. Among the options, the live attenuated vaccine contains live but weakened pathogens that can potentially cause disease in immune compromised individuals.

Step 4: Recognize that vaccines like mRNA, whole inactivated, toxoid, and conjugate vaccines do not contain live organisms and are generally safer for immune compromised patients.

Step 5: Conclude that the vaccine most likely contraindicated for immune compromised patients is the live attenuated vaccine due to the risk of causing infection.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.

영상 길이:

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Types of Vaccines

Vaccines can be classified based on their composition and mechanism, including live attenuated, inactivated, toxoid, conjugate, and mRNA vaccines. Each type stimulates the immune system differently, influencing their safety and efficacy profiles, especially in vulnerable populations.

Live Attenuated Vaccines and Immunocompromised Patients

Live attenuated vaccines contain weakened but live pathogens that can replicate in the host. While effective in healthy individuals, they pose a risk to immunocompromised patients because the weakened pathogen may cause disease due to the patient’s reduced immune defense.

Contraindications in Immunocompromised Individuals

Contraindications are conditions or factors that make a particular treatment unsafe. In immunocompromised patients, vaccines that contain live organisms are generally contraindicated to avoid potential infection, whereas inactivated or subunit vaccines are considered safer alternatives.

Which of the following vaccines is most likely to be contraindicated for an immune compromised patient?a. An mRNA vaccineb. A whole inactivated vaccinec. A toxoid vaccined. A conjugate vaccinee. A live attenuated vaccine