Why does Duchenne Muscular Dystrophy (DMD) primarily affect boys, and what type of inheritance pattern does it follow?
A
DMD is an X-linked recessive disorder, affecting boys because they have only one X chromosome.
B
DMD is an autosomal dominant disorder, affecting boys due to random mutation.
C
DMD is an autosomal recessive disorder, affecting boys due to a higher mutation rate in males.
D
DMD is a Y-linked disorder, affecting boys because it is passed from father to son.
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1
Understand the basics of Duchenne Muscular Dystrophy (DMD): It is a genetic disorder characterized by progressive muscle degeneration and weakness.
Recognize the inheritance pattern: DMD is an X-linked recessive disorder. This means the gene causing the disorder is located on the X chromosome.
Consider the genetic makeup of males and females: Males have one X and one Y chromosome (XY), while females have two X chromosomes (XX).
Analyze why DMD primarily affects boys: Since males have only one X chromosome, a single recessive gene on the X chromosome will result in the disorder. Females would need two copies of the recessive gene to be affected, which is less likely.
Conclude the inheritance pattern: DMD follows an X-linked recessive pattern, explaining why it predominantly affects boys.