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Multiple Choice
Which of the following is incorrect regarding DNA replication forks?
A
DNA replication forks begin forming at the origin of replication (ORI).
B
DNA replication forks are caused by helicase separating two complementary strands of DNA.
C
There are two replication forks found in each replicating prokaryotic chromosome.
D
DNA replication forks are found at both ends of the replication 'bubble'.
E
None of the above are incorrect.
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검증된 단계별 안내
1
Understand the concept of DNA replication forks: DNA replication forks are structures that form during the process of DNA replication. They are created when the enzyme helicase unwinds the double-stranded DNA, separating the two strands to allow replication to occur.
Identify the origin of replication (ORI): The ORI is a specific sequence in the genome where DNA replication begins. Replication forks form at the ORI as helicase unwinds the DNA.
Recognize the role of helicase: Helicase is an enzyme that unwinds the DNA double helix, creating replication forks by separating the two complementary strands of DNA.
Examine the replication process in prokaryotes: In prokaryotic cells, such as bacteria, the chromosome is typically circular. When replication begins, two replication forks are formed, moving in opposite directions around the circular chromosome.
Understand the replication 'bubble': As helicase unwinds the DNA, a replication 'bubble' forms, with replication forks at each end. This allows the DNA polymerase enzymes to synthesize new DNA strands in both directions.