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Advanced Anatomy & Physiology: Reproductive System

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  • Sexual reproduction

    Process by which organisms produce offspring.

  • Sex determination

    Sperm determines sex of child: XX = female, XY = male.

  • Functions of testes and ovaries

    Produce gametes (sperm/oocyte) and secrete sex hormones.

  • Seminiferous tubules

    Tightly coiled tubes in testes where sperm are produced.

  • Temperature requirement for sperm production

    Requires temperature about 2-3°C below core body temperature.

  • Epididymis functions

    Reabsorbs degenerated sperm, site of sperm maturation, and stores sperm for months.

  • Ductus (vas) deferens function

    Conveys sperm during arousal by peristaltic contractions and stores sperm.

  • Seminal vesicles contribution to semen

    Produce about 60% of semen; secrete alkaline fluid, fructose, clotting proteins, and prostaglandins.

  • Prostate gland secretions

    Contributes ~30% of semen; secretes citric acid, proteolytic enzymes, and seminalplasmin (antibiotic).

  • Bulbourethral (Cowper’s) glands

    Secrete alkaline fluid and mucus to neutralize and lubricate urethra for sperm protection.

  • Penis anatomy

    Contains erectile tissue; passageway for ejaculation and urine excretion; includes glans and prepuce (foreskin).

  • Mechanism of erection

    Parasympathetic fibers release nitric oxide (NO) causing arteriole dilation and blood engorgement.

  • Sperm structure

    Head contains nucleus (DNA) and acrosome; midpiece has mitochondria; tail (flagellum) enables movement.

  • Male puberty hormonal control

    FSH stimulates spermatogenesis; LH stimulates testosterone production; controlled by GnRH from hypothalamus.

  • Role of Sertoli cells

    Support spermatogenic cells, form blood-testis barrier, nourish sperm, secrete androgen-binding protein and inhibin.

  • Mitosis vs Meiosis

    Mitosis produces identical diploid cells; meiosis produces haploid gametes with genetic variation via crossing over.

  • Stages of spermatogenesis

    Spermatogonia (2n) → primary spermatocytes (2n) → secondary spermatocytes (n) → spermatids (n) → sperm (mature).

  • Oogenesis overview

    Formation of female gametes; primary oocytes begin meiosis before birth; secondary oocyte released at ovulation.

  • Follicular development stages

    Primordial → primary → secondary → mature (Graafian) follicle; ovulation releases secondary oocyte.

  • Corpus luteum function

    Forms after ovulation; secretes progesterone, estrogens, relaxin, and inhibin to maintain endometrium.

  • Phases of uterine cycle

    Menstrual, proliferative (preovulatory), ovulation, and secretory (postovulatory) phases.

  • Hormonal regulation of female cycle

    GnRH stimulates FSH and LH; FSH promotes follicle growth; LH triggers ovulation and corpus luteum formation.

  • Estrogen functions

    Promote female reproductive development, secondary sex characteristics, increase protein synthesis, and lower blood cholesterol.

  • Progesterone functions

    Prepares and maintains endometrium for implantation; inhibits GnRH and LH secretion; supports mammary gland development.

  • Relaxin role

    Relaxes uterine muscles, increases pubic symphysis flexibility, and softens uterine cervix during pregnancy.

  • Inhibin function

    Secreted by granulosa cells and corpus luteum; inhibits secretion of FSH and LH.