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Basic Chemistry Concepts in Anatomy & Physiology

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  • What is matter?

    Matter is anything that has mass and occupies space. It can be seen, smelled, or felt.

  • Name the three states of matter and their characteristics.

    Solid: definite shape and volume.
    Liquid: changeable shape, definite volume.
    Gas: changeable shape and volume.

  • Define energy and its two main forms.

    Energy is the capacity to do work or put matter into motion.
    Kinetic energy: energy in action.
    Potential energy: stored (inactive) energy.

  • List the four main forms of energy relevant to physiology.

    Chemical (stored in bonds), Electrical (movement of charged particles), Mechanical (directly moves matter), Radiant/Electromagnetic (travels in waves like light).

  • What are elements and which four make up 96% of the human body?

    Elements are substances that cannot be broken down by ordinary chemical means.
    The four main elements are carbon, oxygen, hydrogen, and nitrogen.

  • Describe the basic structure of an atom.

    Atoms consist of protons (+, 1 amu) and neutrons (0, 1 amu) in the nucleus, with electrons (−, ~0 amu) orbiting the nucleus.

  • What is the atomic number and mass number of an atom?

    Atomic number: number of protons.
    Mass number: total protons and neutrons.

  • Define isotopes and radioisotopes.

    Isotopes: atoms of the same element with different neutrons.
    Radioisotopes: unstable isotopes that emit energy as they decay.

  • What is a molecule, compound, and mixture?

    Molecule: two or more atoms bonded.
    Compound: molecule with different atoms.
    Mixture: physical combination of substances.

  • Name and describe the three types of mixtures.

    Solutions: homogeneous, solute particles do not settle.
    Colloids: heterogeneous, larger particles, do not settle.
    Suspensions: heterogeneous, large particles settle out.

  • How is solution concentration expressed?

    Concentration is expressed as percent, mg/dL, or molarity (M). 1 mole equals molecular weight in grams.

  • What is the difference between mixtures and compounds?

    Mixtures do not involve chemical bonding and can be separated physically; compounds involve chemical bonds and require chemical means to separate.

  • What is the valence shell and the octet rule?

    The valence shell is the outermost electron shell involved in bonding.
    The octet rule states atoms seek 8 electrons in their valence shell (except H and He, which seek 2).

  • Describe ionic bonds.

    Ionic bonds form by transfer of electrons, creating oppositely charged ions that attract (e.g., NaCl).

  • Describe covalent bonds and their types.

    Covalent bonds involve sharing electrons.
    Nonpolar: equal sharing (e.g., CO2).
    Polar: unequal sharing causing partial charges (e.g., H2O).

  • What are hydrogen bonds and their importance?

    Hydrogen bonds are weak attractions between electropositive hydrogen and electronegative atoms, important for water properties and molecular structure.

  • What is a synthesis (combination) reaction?

    Atoms or molecules combine to form larger molecules. General form: A + B → AB.

  • What is a decomposition reaction?

    A molecule breaks down into smaller parts. General form: AB → A + B.

  • What is an exchange (displacement) reaction?

    Bonds are both made and broken. General forms: AB + C → AC + B or AB + CD → AD + CB.

  • Define redox (oxidation-reduction) reactions.

    Electrons are transferred between atoms. Oxidation is loss of electrons; reduction is gain of electrons.

  • What is the difference between exergonic and endergonic reactions?

    Exergonic: release energy (products have less energy).
    Endergonic: absorb energy (products have more energy).

  • What factors affect the rate of chemical reactions?

    Temperature, concentration, particle size, and catalysts affect reaction rate.

  • What is the role of catalysts in chemical reactions?

    Catalysts increase reaction rate without being changed; enzymes are biological catalysts.