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Respiratory System 22.1

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  • Primary functions of the respiratory system

    Provide oxygen for cellular respiration, remove carbon dioxide, and maintain acid-base balance.
  • Conducting zone of the respiratory system

    Includes organs and structures that provide a route for air, remove debris, and warm and humidify incoming air.
  • Respiratory zone of the respiratory system

    Structures directly involved in gas exchange, including respiratory bronchioles, alveolar ducts, and alveoli.
  • External nose components

    Root, bridge, dorsum nasi, apex, alae (cartilaginous sides of nostrils), nostrils (nares), and philtrum.
  • Nasal septum composition

    Anteriorly septal cartilage; posteriorly perpendicular plate of ethmoid bone and vomer bone.
  • Function of nasal conchae

    Increase surface area, disrupt airflow to warm, humidify, and trap debris in the nasal cavity.
  • Paranasal sinuses function

    Warm and humidify air, produce mucus, and lighten the skull's weight.
  • Respiratory epithelium characteristics

    Pseudostratified ciliated columnar epithelium with goblet cells that produce mucus and cilia that move debris toward the throat.
  • Pharynx divisions

    Nasopharynx (air only), oropharynx (air and food), and laryngopharynx (air and food, leads to esophagus and larynx).
  • Pharyngeal tonsils (adenoids)

    Lymphoid tissue in nasopharynx that traps and destroys pathogens; large in children and regress with age.
  • Role of the uvula and soft palate during swallowing

    Swing upward to close off the nasopharynx, preventing food from entering the nasal cavity.
  • Larynx major cartilages

    Thyroid cartilage (largest), epiglottis (elastic cartilage covering trachea), and cricoid cartilage (ring-shaped).
  • True vocal cords

    Membranous folds attached to thyroid and arytenoid cartilages that vibrate to produce sound.
  • Function of the epiglottis

    Covers the tracheal opening during swallowing to prevent food and liquids from entering the airway.
  • Trachea structure

    16-20 C-shaped hyaline cartilage rings connected by fibroelastic membrane and trachealis muscle; lined with pseudostratified ciliated columnar epithelium.
  • Bronchial tree

    Branching system of bronchi and bronchioles that conduct air into the lungs; lined with mucus-producing epithelium and supported by cartilage.
  • Difference between bronchi and bronchioles

    Bronchi have cartilage rings; bronchioles lack cartilage and have muscular walls to regulate airflow.
  • Alveoli function

    Small sacs where gas exchange occurs between air and blood.
  • Type I alveolar cells

    Squamous epithelial cells covering 97% of alveolar surface; thin for gas diffusion.
  • Type II alveolar cells

    Secrete pulmonary surfactant to reduce alveolar surface tension and prevent collapse.
  • Alveolar macrophages

    Phagocytic immune cells that remove debris and pathogens in alveoli.
  • Respiratory membrane

    Thin barrier (~0.5 μm) formed by alveolar and capillary walls allowing gas diffusion.
  • Asthma characteristics

    Chronic inflammation, edema, bronchospasms, and excessive mucus secretion causing airway obstruction.
  • Common asthma triggers

    Dust, pollen, pet dander, weather changes, mold, tobacco smoke, infections, exercise, and stress.
  • Symptoms of an asthma attack

    Coughing, wheezing, shortness of breath, chest tightness; severe attacks cause cyanosis, confusion, and rapid pulse.
  • Asthma treatment methods

    Short-term fast-acting inhalers or nebulizers; long-term medications for severe cases.
  • Role of cilia in respiratory epithelium

    Beat mucus upward to the throat to remove trapped debris and pathogens.
  • Why cold air causes runny nose

    Cold air slows cilia movement, causing mucus accumulation and nasal discharge.