In anaerobic glycolysis (conversion of one glucose to two pyruvate), what is the net gain of energy in terms of ATP and NADH produced per glucose molecule?
A
Net gain: 2 ATP and 2 NADH
B
Net gain: 2 ATP and 0 NADH
C
Net gain: 0 ATP and 2 NADH
D
Net gain: 4 ATP and 2 NADH
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1
Recall that anaerobic glycolysis converts one molecule of glucose into two molecules of pyruvate through a series of enzymatic steps.
Identify the ATP molecules consumed and produced during glycolysis: 2 ATP are used in the initial energy investment phase, and 4 ATP are produced in the payoff phase.
Calculate the net ATP gain by subtracting the ATP used from the ATP produced: Net ATP = 4 ATP produced - 2 ATP consumed.
Determine the NADH production: During glycolysis, 2 molecules of NAD+ are reduced to 2 NADH molecules per glucose molecule.
Summarize the net energy yield per glucose molecule in anaerobic glycolysis as the net ATP gain and the total NADH produced.