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Multiple Choice
Which of the following is a defining feature of aerobic metabolism in human cells?
A
ATP generation primarily by photophosphorylation in mitochondria
B
Use of pyruvate as the terminal electron acceptor to regenerate during fermentation
C
Use of as the terminal electron acceptor in the electron transport chain, enabling oxidative phosphorylation
D
Direct substrate-level phosphorylation as the primary mechanism for ATP production in the cytosol
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1
Identify the key characteristics of aerobic metabolism in human cells, focusing on how ATP is generated and what electron acceptors are involved.
Recall that aerobic metabolism involves the electron transport chain located in mitochondria, where oxygen (O\_2) acts as the final electron acceptor.
Understand that oxidative phosphorylation is the process by which ATP is produced in mitochondria using the proton gradient generated by the electron transport chain.
Contrast aerobic metabolism with fermentation, where pyruvate is used as the terminal electron acceptor to regenerate NAD\^+ in the absence of oxygen.
Recognize that photophosphorylation occurs in photosynthetic organisms, not human cells, and that substrate-level phosphorylation in the cytosol is important but not the primary ATP source in aerobic metabolism.