객관식
The advantage of the pentose phosphate pathway is that it produces all of the following except:
144
views
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Pentose Phosphate Pathway
객관식
In the pentose phosphate pathway, which enzyme catalyzes the first committed step, resulting in the production of 6-phosphoglucono-δ-lactone from glucose-6-phosphate?
A
Aldolase
B
Transketolase
C
Phosphoglucomutase
D
Glucose-6-phosphate dehydrogenase
검증된 단계별 안내1
Understand the pentose phosphate pathway: This metabolic pathway is crucial for producing NADPH and ribose-5-phosphate, which are essential for biosynthetic reactions and nucleotide synthesis, respectively.
Identify the first committed step: The first committed step is the irreversible reaction that commits glucose-6-phosphate to the pentose phosphate pathway. This step is catalyzed by the enzyme glucose-6-phosphate dehydrogenase.
Describe the reaction: Glucose-6-phosphate dehydrogenase catalyzes the oxidation of glucose-6-phosphate, resulting in the production of 6-phosphoglucono-δ-lactone and NADPH. The reaction can be represented as:
Explain the role of glucose-6-phosphate dehydrogenase: This enzyme is highly regulated and serves as the rate-limiting step of the pentose phosphate pathway. It ensures that glucose-6-phosphate is directed into the pathway when NADPH is needed.
Clarify why other enzymes are incorrect: Aldolase is involved in glycolysis, transketolase is involved in the non-oxidative phase of the pentose phosphate pathway, and phosphoglucomutase is involved in glycogen metabolism. None of these enzymes catalyze the first committed step of the pentose phosphate pathway.
관련 영상
관련 실천
