what-role-do-the-dissociation-rate-constant-k-esi-and-association-rate-constant-

Question

What role do the dissociation rate constant (k-ESI) and association rate constant (kESI) play in determining the inhibition constant (K'I) for the enzyme-substrate-inhibitor complex?

Accepted Answer

They determine the ratio that defines the inhibition constant (K'I).

Answer

They determine the substrate concentration required for half-maximal inhibition.

Answer

They determine the enzyme concentration required for complete inhibition.

Answer

They determine the maximum reaction velocity of the enzyme-substrate-inhibitor complex.