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Peripheral Membrane Proteins definitions

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  • Lipid Bilayer
    Structure composed of two layers of phospholipids forming the fundamental framework of cellular membranes.
  • Peripheral Membrane Protein
    Molecule loosely attached to the membrane surface, easily removed by changes in pH or ionic strength.
  • Integral Membrane Protein
    Molecule embedded within the membrane, tightly associated through hydrophobic interactions.
  • Electrostatic Interaction
    Attraction between charged groups, enabling association of certain proteins with membrane surfaces.
  • Hydrogen Bonding
    Weak interaction involving hydrogen atoms, facilitating protein association with membrane polar head groups.
  • Phospholipid
    Amphipathic molecule forming the main component of cellular membranes, with polar heads and fatty acid tails.
  • Polar Head Group
    Hydrophilic region of a phospholipid, interacting with proteins through electrostatic and hydrogen bonds.
  • Fatty Acid Chain
    Hydrophobic tail of a phospholipid, involved in membrane structure and integral protein association.
  • Extracellular Side
    Region outside the cell membrane where certain proteins can associate with the membrane.
  • Intracellular Side
    Region inside the cell membrane, including the cytosol, where proteins may interact with the membrane.
  • Cytosol
    Aqueous solution within cells, allowing certain proteins to diffuse away from the membrane.
  • Amphitropic Protein
    Type of protein capable of associating with the membrane or diffusing freely in the cytosol.
  • Ionic Strength
    Measure of ion concentration in solution, affecting the association of certain proteins with membranes.