The immune response to the throat infection mistakenly attacks heart tissue due to molecular mimicry between streptococcal proteins and heart proteins.
What does the mimicry of streptococcal proteins to human heart proteins tell us about amino acid sequences?
Similar amino acid sequences can produce similar 3D structures, leading to immune cross-reactivity.
What is incorrect about the statement: 'Different proteins always have different sequences'?
Proteins can have similar sequences or motifs that result in similar structures, so this statement is false.
What does the immune system recognize in proteins?
The immune system recognizes protein shape (3D structure), not just the amino acid sequence.
Are streptococcal proteins identical to human proteins?
No, they are not identical but can have similar sequences that mimic human proteins.
Which protein function category does immunoglobulin belong to?
Immunoglobulins belong to the protein function category of immune defense proteins.
How did immunoglobulin fail Jordan?
Immunoglobulin failed by mistakenly targeting the heart due to molecular mimicry, causing autoimmune damage.