Acetylcholinesterase is the enzyme that degrades acetylcholine. What effect on nerve transmission would occur following the administration of a chemical that inhibited acetylcholinesterase?
A
There would be no effect.
B
Synaptic transmission would be prevented; muscle paralysis would occur.
C
It would be identical to giving an anesthetic, but it would last permanently.
D
The presynaptic neuron would be inactivated.
E
Continuous excitatory postsynaptic potentials would occur in the postsynaptic neuron.
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1
Understand the role of acetylcholine in nerve transmission: Acetylcholine is a neurotransmitter that facilitates communication between neurons and muscles at synapses.
Learn about acetylcholinesterase: This enzyme breaks down acetylcholine in the synaptic cleft, terminating the signal transmission and allowing the neuron to reset for the next signal.
Consider the effect of inhibiting acetylcholinesterase: If acetylcholinesterase is inhibited, acetylcholine will not be broken down efficiently, leading to prolonged presence in the synaptic cleft.
Analyze the consequences of prolonged acetylcholine presence: Continuous stimulation of the postsynaptic neuron occurs, resulting in sustained excitatory postsynaptic potentials.
Conclude the effect on nerve transmission: The inhibition of acetylcholinesterase leads to continuous excitatory postsynaptic potentials, causing persistent activation of the postsynaptic neuron.