Which of the following DNA repair systems can detect and correct damaged or altered DNA bases?
A
Base Excision Repair
B
Nucleotide Excision Repair
C
Homologous Recombination
D
Mismatch Repair
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Understand the types of DNA damage: DNA can be damaged by various factors such as UV light, chemicals, and radiation, leading to altered or incorrect bases.
Learn about Base Excision Repair (BER): This system specifically targets and repairs damaged or altered DNA bases. It involves the removal of the damaged base by a DNA glycosylase enzyme, followed by the cutting of the DNA backbone by an endonuclease.
Explore Nucleotide Excision Repair (NER): This system is designed to repair bulky lesions in DNA, such as those caused by UV light. It removes a short single-stranded DNA segment containing the damage and fills in the gap with new nucleotides.
Understand Homologous Recombination: This repair system is primarily involved in repairing double-strand breaks in DNA, using a homologous sequence as a template for repair.
Learn about Mismatch Repair: This system corrects errors that occur during DNA replication, such as mismatched bases, by recognizing and repairing the incorrect pairing.