If one molecule of glucose undergoes the reaction of glycolysis, what is the net gain of ATP molecules produced?
A
4 ATP
B
6 ATP
C
8 ATP
D
2 ATP
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1
Understand the process of glycolysis: Glycolysis is the metabolic pathway where one molecule of glucose (C₆H₁₂O₆) is broken down into two molecules of pyruvate. This occurs in the cytoplasm and does not require oxygen.
Identify the ATP usage and production during glycolysis: Glycolysis involves an initial investment of 2 ATP molecules during the energy investment phase to phosphorylate glucose and prepare it for breakdown.
Calculate the ATP produced during the energy payoff phase: During glycolysis, 4 ATP molecules are generated in the energy payoff phase through substrate-level phosphorylation.
Determine the net ATP gain: Subtract the 2 ATP molecules used in the energy investment phase from the 4 ATP molecules produced in the energy payoff phase. The net gain is calculated as \( \text{Net ATP} = 4 - 2 \).
Conclude the net ATP gain: The net gain of ATP molecules from one molecule of glucose undergoing glycolysis is 2 ATP.