The first level of DNA organization in a eukaryotic cell is maintained by which molecule?
A
Topoisomerase
B
Histones
C
RNA polymerase
D
DNA ligase
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1
Understand that DNA organization in eukaryotic cells involves the packaging of DNA into a compact, organized structure to fit within the nucleus.
Recognize that histones are proteins that play a crucial role in the first level of DNA organization by forming a complex with DNA.
Learn that DNA wraps around histone proteins to form nucleosomes, which are the basic units of chromatin structure.
Differentiate between the roles of other molecules listed: Topoisomerase alters the supercoiling of DNA, RNA polymerase synthesizes RNA from a DNA template, and DNA ligase joins DNA fragments.
Conclude that histones are responsible for the initial packaging of DNA into chromatin, making them the correct answer for the first level of DNA organization.