객관식
What determines how long a particular mRNA molecule will persist in a eukaryotic cell?
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16. Regulation of Expression
Eukaryotic Post-Transcriptional Regulation
객관식
MicroRNAs and small interfering RNAs both function similarly in "silencing" genes. What are two ways in which they may act?
A
Inhibit RNA splicing and bind to complementary DNA sequences to prevent transcription
B
Cut up mRNAs using the Dicer enzyme and bind to complementary mRNA sequences to prevent translation
C
Cut up mRNAs using the Dicer enzyme and bind to complementary DNA sequences to prevent transcription
D
Promote the degradation of mRNA and inhibit RNA splicing
E
Promote the degradation of mRNA and bind to complementary mRNA sequences to prevent translation
검증된 단계별 안내1
Understand the role of microRNAs (miRNAs) and small interfering RNAs (siRNAs) in gene silencing. Both are involved in post-transcriptional regulation of gene expression.
Recognize that miRNAs and siRNAs can bind to complementary mRNA sequences. This binding typically results in the prevention of translation, effectively silencing the gene.
Identify that one mechanism of action is the promotion of mRNA degradation. When miRNAs or siRNAs bind to their target mRNA, they can recruit cellular machinery that degrades the mRNA, preventing it from being translated into protein.
Note that the Dicer enzyme is involved in the processing of miRNAs and siRNAs, but it is not directly responsible for cutting up mRNAs. Instead, it processes precursor RNA molecules into mature miRNAs or siRNAs.
Conclude that the two main ways miRNAs and siRNAs act are by promoting the degradation of mRNA and by binding to complementary mRNA sequences to prevent translation, aligning with the correct answer provided.
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