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Multiple Choice
What is true about the lagging strand during DNA replication?
A
It is synthesized continuously in the 5' to 3' direction.
B
It is synthesized in short segments called Okazaki fragments.
C
It is synthesized in the 3' to 5' direction.
D
It requires only one RNA primer for synthesis.
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검증된 단계별 안내
1
Understand the directionality of DNA strands: DNA strands have directionality, with one end being the 5' end and the other the 3' end. DNA polymerase synthesizes new DNA strands in the 5' to 3' direction.
Differentiate between leading and lagging strands: During DNA replication, the leading strand is synthesized continuously in the 5' to 3' direction, while the lagging strand is synthesized discontinuously.
Learn about Okazaki fragments: The lagging strand is synthesized in short segments known as Okazaki fragments. These fragments are later joined together by the enzyme DNA ligase.
Understand the role of RNA primers: The synthesis of the lagging strand requires multiple RNA primers. Each Okazaki fragment begins with an RNA primer, which provides a starting point for DNA polymerase.
Clarify the synthesis direction: Although the lagging strand is synthesized in the 5' to 3' direction, it appears to be synthesized in the opposite direction due to the discontinuous nature of Okazaki fragments.