Ibuprofen is known for its pain-relieving and anti-inflammatory properties because it inhibits the synthesis of __________.
A
epinephrine
B
nitric oxide
C
steroid hormones
D
estrogens
E
prostaglandins
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1
Understand the role of ibuprofen: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce pain, fever, and inflammation.
Identify the biological pathway affected by ibuprofen: Ibuprofen works by inhibiting the enzyme cyclooxygenase (COX), which is crucial in the conversion of arachidonic acid to prostaglandins.
Recognize the function of prostaglandins: Prostaglandins are lipid compounds that have several important roles in the body, including mediating inflammation and pain.
Connect the inhibition of COX to the reduction of prostaglandins: By inhibiting COX, ibuprofen effectively reduces the production of prostaglandins, leading to decreased inflammation and pain.
Conclude that the synthesis of prostaglandins is inhibited by ibuprofen, which explains its pain-relieving and anti-inflammatory properties.