First, identify the function you need to differentiate: f(x) = 6x^4 - 4^3.
Recognize that the function is a polynomial, and apply the power rule for differentiation. The power rule states that if f(x) = ax^n, then f'(x) = n * ax^(n-1).
Apply the power rule to the term 6x^4. Differentiate it to get: f'(x) = 4 * 6x^(4-1).
The term -4^3 is a constant, and the derivative of a constant is zero. Therefore, it does not contribute to the derivative.
Combine the results from the differentiation: f'(x) = 24x^3.