Which of the following is NOT a subunit of a typical heterotrimeric G protein?
A
Gamma subunit
B
Beta subunit
C
Alpha subunit
D
Delta subunit
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1
Understand the structure of a heterotrimeric G protein: It is composed of three subunits—alpha (α), beta (β), and gamma (γ). These subunits work together to mediate signal transduction in cells.
Recall that the alpha subunit (α) binds and hydrolyzes GTP, playing a key role in activating or deactivating the G protein.
The beta (β) and gamma (γ) subunits form a stable dimer that helps anchor the G protein to the plasma membrane and assists in signaling.
Note that there is no 'delta (δ)' subunit in the structure of a typical heterotrimeric G protein. This is a distractor in the question.
Conclude that the delta (δ) subunit is NOT a part of a heterotrimeric G protein, as it does not exist in this context.