In early mammalian development, the inner cell mass (ICM) of the blastocyst will primarily give rise to which structure(s)?
A
A single adult tissue type because its cells are already terminally differentiated
B
Only the trophoblast layer that later forms the chorion
C
The embryo proper (and some extraembryonic tissues), forming all three germ layers
D
Only the placenta and other extraembryonic membranes
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1
Understand the context: The inner cell mass (ICM) is a group of cells inside the blastocyst during early mammalian development.
Recall the fate of the ICM: The ICM cells are pluripotent, meaning they can give rise to multiple cell types but are not yet terminally differentiated.
Identify the structures derived from the ICM: The ICM primarily forms the embryo proper, which includes all three germ layers—ectoderm, mesoderm, and endoderm—as well as some extraembryonic tissues.
Differentiate the ICM from the trophoblast: The trophoblast layer, which is separate from the ICM, contributes mainly to the placenta and other extraembryonic membranes.
Conclude that the ICM does not form only a single adult tissue type or only extraembryonic structures, but rather the entire embryo proper and some supporting tissues.