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Cell-Cell Adhesion definitions

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  • Cell Adhesion
    Process ensuring neighboring cells stick together, maintaining tissue and organ structure and function.
  • Homophilic Interaction
    Connection between cells using identical molecules on both cell surfaces, common in tissues.
  • Heterophilic Interaction
    Connection between cells using different molecules on each cell surface, allowing diverse cell contacts.
  • Cell Adhesion Molecule
    Protein embedded in the plasma membrane, essential for connecting adjacent cells in tissues.
  • Cadherin
    Glycoprotein in the plasma membrane, requiring calcium, crucial for binding cells together in tissues.
  • Glycoprotein
    Protein with attached sugar groups, often found in cell membranes, facilitating cell interactions.
  • Plasma Membrane
    Cell boundary where adhesion proteins reside, enabling direct contact with neighboring cells.
  • Epithelial-Mesenchymal Transition
    Developmental process where cells change type, essential for forming tissues like blood, muscle, or bone.
  • Endothelial Cadherin
    Classical cadherin type primarily interacting with cells lining blood vessels.
  • Placental Cadherin
    Classical cadherin type mainly associated with placental tissue interactions.
  • Neural Cadherin
    Classical cadherin type predominantly found in neural tissue, supporting nervous system structure.
  • Lectin
    Protein that binds specifically to sugars, mediating heterophilic cell adhesion.
  • Selectin
    Glycoprotein involved in white blood cell adhesion, crucial for inflammation and immune response.
  • Endothelial Selectin
    Selectin class found on blood vessel cells, facilitating leukocyte movement during inflammation.
  • Platelet Selectin
    Selectin class present on platelets, playing a role in blood clotting and immune cell recruitment.
  • Leukocyte Selectin
    Selectin class located on white blood cells, aiding their interaction with blood vessel walls.