Recall that the number of neutrons in an isotope is given by the difference between the mass number (A) and the atomic number (Z): \(\text{Number of neutrons} = A - Z\).
Identify the mass number (the number after the element name) and the atomic number (given for each element) for each isotope option.
Calculate the number of neutrons for Titanium-45: \(45 - 22\).
Calculate the number of neutrons for Scandium-66: \(66 - 21\).
Calculate the number of neutrons for Vanadium-68: \(68 - 23\), and for Calcium-45: \(45 - 20\), then compare all results to find which isotope has exactly 45 neutrons.