Understand the structure of DNA: DNA is composed of two long strands forming a shape that resembles a twisted ladder.
Recall the terminology used to describe DNA's shape: The term 'double helix' refers to two strands twisted around each other.
Differentiate between the options: 'Nucleotides' are the building blocks of DNA, not the shape; '3-D model' is a general term; 'Single strand' refers to only one strand, not the twisted ladder shape.
Recognize that the 'double helix' accurately describes the twisted ladder shape formed by two strands of DNA.
Conclude that the correct term for the twisted ladder shape of DNA is the 'double helix'.