객관식
Which molecule is first folded into a hairpin structure during the mechanism of RNA interference?
97
views
10. Transcription
RNA Interference
객관식
In RNA interference (RNAi), how do microRNAs (miRNAs) primarily function to control gene expression in animals?
A
They bind directly to DNA promoter regions to block RNA polymerase II binding and prevent transcription initiation.
B
They act as tRNA-like adaptor molecules that change codon recognition during translation to alter protein sequence.
C
They are translated into small peptides that inhibit ribosome assembly on specific mRNAs.
D
They are processed and loaded into RISC, then base-pair with target mRNAs (usually imperfectly) to repress translation and/or promote mRNA degradation.
검증된 단계별 안내1
Understand that microRNAs (miRNAs) are small non-coding RNA molecules involved in post-transcriptional regulation of gene expression in animals.
Recognize that miRNAs do not bind directly to DNA or affect transcription initiation; instead, they function after mRNA has been produced.
Know that miRNAs are processed from precursor transcripts and incorporated into a protein complex called the RNA-induced silencing complex (RISC).
Learn that within RISC, miRNAs base-pair with complementary sequences on target messenger RNAs (mRNAs), usually with imperfect matching in animals.
Realize that this base-pairing leads to repression of translation and/or promotion of mRNA degradation, thereby reducing the expression of the target gene.
관련 영상
관련 실천
