At the end of which stage of meiosis will there be twice the number of chromatids compared to the beginning?
A
Anaphase II
B
Metaphase II
C
Telophase I
D
S phase (prior to meiosis I)
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1
Recall that the number of chromatids doubles during the S phase of the cell cycle because DNA replication occurs, resulting in each chromosome consisting of two sister chromatids.
Understand that meiosis consists of two divisions: meiosis I and meiosis II, with stages including prophase, metaphase, anaphase, and telophase in each division.
Recognize that at the beginning of meiosis I (after S phase), the cell has chromosomes each made of two sister chromatids, so the chromatid number is doubled compared to before S phase.
Note that during meiosis I, homologous chromosomes separate, but sister chromatids remain together, so the number of chromatids does not double further during meiosis I stages like telophase I.
Conclude that the stage at which the number of chromatids is twice the original (pre-S phase) is actually after the S phase, before meiosis I begins, not during any stage of meiosis itself.