객관식
In the context of epigenetic regulation, what effect does DNA methylation (typically addition of a methyl group to cytosine in CpG dinucleotides) most commonly have on gene expression?
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13. Gene Regulation in Eukaryotes
Epigenetics, Chromatin Modifications, and Regulation
객관식
Which of the following are examples of epigenetic marks?
A
Acetylated guanines in DNA
B
Methylated nucleotides in histone tails
C
Methylated amino acids in histone tails
D
All of the above
검증된 단계별 안내1
Understand the concept of epigenetic marks: Epigenetic marks are chemical modifications that occur on DNA or histone proteins, affecting gene expression without altering the DNA sequence.
Identify common types of epigenetic marks: The most common epigenetic marks include DNA methylation and histone modifications such as methylation, acetylation, and phosphorylation.
Evaluate the options given: Acetylation typically occurs on histone proteins, not on DNA nucleotides like guanine. Methylation can occur on both DNA and histone proteins.
Consider the role of histone tail modifications: Histone tails can be modified by methylation, which is a recognized epigenetic mark affecting chromatin structure and gene expression.
Determine the correct examples: Methylated amino acids in histone tails are a valid example of epigenetic marks, while acetylated guanines in DNA are not typically recognized as such.
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