Which of the following amino acid pairs are the most likely to form hydrogen bonds?

For each amino acid listed, tell whether its influence on tertiary structure is largely through hydrophobic interactions, hydrogen bonding, formation of salt bridges, covalent bonding, or some combination of these effects.

a. Tyrosine

What type of R group interaction is the most likely between the alanine and isoleucine residues?

Oxytocin is a small peptide that is used to induce labor by causing contractions in uterine walls. It has the primary structure Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gln. This peptide is held in a cyclic configuration by a disulfide bridge. Draw a diagram of oxytocin, showing the disulfide bridge.

How do the following noncovalent interactions help to stabilize the tertiary and quaternary structure of a protein? Give an example of a pair of amino acids that could give rise to each interaction.

a. Hydrophobic interactions

Which of the following amino acid pairs can form a salt bridge?

Both α-keratin and tropocollagen have helical secondary structure. How do these molecules differ in (a) amino acid composition and (b) three-dimensional structure?

Identify the amino acids and type of interaction that occurs between the following R groups in tertiary protein structures:

a.

Identify the amino acids and type of interaction that occurs between the following R groups in tertiary protein structures:

c. —CH₂—SH and HS—CH₂—