Haemophilus influenzae is an encapsulated, pathogenic bacterium which causes meningitis in infants and young children. What type of vaccine would be best to protect young children from this disease?
A
Conjugate vaccine.
B
Toxoid vaccine.
C
Attenuated vaccine.
D
Polysaccharide vaccine.
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검증된 단계별 안내
1
Step 1: Understand the nature of Haemophilus influenzae, which is an encapsulated bacterium. The capsule is made of polysaccharides that help the bacterium evade the immune system, making it a key target for vaccine development.
Step 2: Recognize that polysaccharide vaccines alone often do not produce a strong immune response in young children because their immune systems do not respond well to polysaccharide antigens without protein help.
Step 3: Learn that conjugate vaccines link the polysaccharide capsule to a protein carrier, which helps stimulate a stronger and longer-lasting immune response, especially in infants and young children.
Step 4: Compare other vaccine types: toxoid vaccines target bacterial toxins, attenuated vaccines use weakened live bacteria, and polysaccharide vaccines use only the capsule polysaccharides without a protein carrier. None of these are as effective for young children against encapsulated bacteria like Haemophilus influenzae.
Step 5: Conclude that the conjugate vaccine is the best choice to protect young children from Haemophilus influenzae meningitis because it effectively induces immunity by combining the polysaccharide capsule with a protein carrier.