What is the outcome when mice are injected with only the R (rough) strain of Streptococcus pneumoniae in the Griffith experiment?
A
The mice remain healthy and survive.
B
The mice develop pneumonia and die.
C
The mice develop a mild infection but recover.
D
The mice die, but no bacteria can be recovered from their bodies.
0 댓글
검증된 단계별 안내
1
Recall the key characteristics of the R (rough) strain of Streptococcus pneumoniae: it lacks a polysaccharide capsule, which makes it non-virulent because it cannot evade the host's immune system effectively.
Understand that in the Griffith experiment, the R strain alone is unable to cause disease in mice because it is recognized and destroyed by the immune system.
Recognize that when mice are injected with only the R strain, they do not develop pneumonia or die, as the bacteria are not virulent without the capsule.
Conclude that the expected outcome is that the mice remain healthy and survive after injection with the R strain alone.
This outcome contrasts with the S (smooth) strain, which has a capsule and causes disease, highlighting the importance of the capsule in virulence.