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Why are small immune complexes damaging to the body?
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- 1. Introduction to Microbiology3h 27m
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27. Immunological Disorders
Type III Hypersensitivities
Multiple Choice
Type III hypersensitivity is caused by the immune system’s reaction to immune complexes. Immune complexes are made of aggregates of which of the following?
A
Immunohemagglutinins and foreign RBCs.
B
AB antigens and Rh antigens found in RBCs.
C
Antigens bound to antibodies in tissues and blood.
D
Multiple complement system proteins binding to form a membrane attack complex.
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검증된 단계별 안내1
Understand that Type III hypersensitivity involves immune complexes, which are formed when antibodies bind to soluble antigens.
Recognize that these immune complexes are aggregates consisting of antigens bound to antibodies, typically found in tissues and blood.
Recall that these complexes can deposit in various tissues, triggering inflammation and tissue damage through complement activation and recruitment of immune cells.
Differentiate this from other options: immunohemagglutinins and foreign RBCs relate to agglutination, AB and Rh antigens are blood group markers, and complement proteins forming membrane attack complexes are part of a different immune mechanism (Type II or direct complement-mediated lysis).
Conclude that the correct description of immune complexes in Type III hypersensitivity is 'antigens bound to antibodies in tissues and blood.'
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