Where do T cells undergo central tolerance selection?
A
Bone marrow.
B
Pancreas.
C
Thymus.
D
Liver.
E
Brain.
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1
Understand the concept of central tolerance: Central tolerance is a process that occurs during the development of immune cells, specifically T cells and B cells, to ensure that they do not attack the body's own tissues.
Identify the location where T cells mature: T cells originate from hematopoietic stem cells in the bone marrow but migrate to the thymus for maturation.
Learn about the role of the thymus: The thymus is a specialized organ where T cells undergo maturation and selection processes, including central tolerance.
Explore the selection process: In the thymus, T cells are exposed to self-antigens. Those that react strongly to self-antigens are eliminated, while those that do not react or react weakly are allowed to mature.
Conclude the location of central tolerance for T cells: Based on the maturation and selection processes, the thymus is the site where T cells undergo central tolerance selection.