객관식
Histone acetylation is associated with:
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15. Central Dogma & Gene Regulation
Eukaryotic Chromatin Modifications
2:26분문제 13
교과서 질문
Which of the following are involved in pre-transcriptional regulation? Select all that apply.
a. Methylation
b. Riboswitches
c. Operons
d. Short interfering RNAs (siRNAs)
e. Transcription factors
검증된 단계별 안내1
Step 1: Understand what pre-transcriptional regulation means. It refers to the control mechanisms that affect gene expression before the process of transcription begins, primarily influencing whether or not a gene is transcribed into RNA.
Step 2: Analyze each option to determine if it acts before transcription starts. Methylation (a) involves adding methyl groups to DNA, often silencing genes by preventing transcription factor binding, so it is a pre-transcriptional mechanism.
Step 3: Riboswitches (b) are RNA elements that regulate gene expression by binding small molecules and affecting transcription or translation after the RNA is made, so they are not pre-transcriptional but rather post-transcriptional or translational regulators.
Step 4: Operons (c) are clusters of genes regulated together at the transcriptional level, involving promoters and operators that control RNA polymerase binding, so operons are involved in pre-transcriptional regulation.
Step 5: Short interfering RNAs (siRNAs) (d) and transcription factors (e) differ: siRNAs act after transcription by degrading mRNA or blocking translation (post-transcriptional), while transcription factors (e) bind DNA to promote or inhibit transcription initiation, making them pre-transcriptional regulators.
비슷한 문제에 대한 검증된 영상 답변:이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
2m주요 개념
질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.
Pre-transcriptional Regulation
Pre-transcriptional regulation refers to mechanisms that control gene expression before the process of transcription begins. This includes modifications to DNA or chromatin structure that affect the accessibility of genes to the transcription machinery, thereby influencing whether a gene is transcribed.
추천 영상:
05:17
1) Alternative RNA Splicing
DNA Methylation
DNA methylation involves adding methyl groups to cytosine bases in DNA, often leading to gene silencing. It is a key epigenetic modification that prevents transcription factors from binding to DNA, thus serving as a pre-transcriptional regulatory mechanism.
추천 영상:
03:39DNA Methylation
Operons
Operons are clusters of genes under the control of a single promoter and regulatory elements, primarily found in prokaryotes. They regulate gene expression at the transcriptional level by enabling coordinated control of multiple genes before transcription starts.
추천 영상:
06:24Review of the Lac Operon & Trp Operon