Hannah is allergic to wasp venom. During a picnic with friends, she is stung by a wasp and has an immediate, rapid, life-threatening response. Which type of hypersensitivity is this?
A
Type I.
B
Type II.
C
Type III.
D
Type IV.
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1
Understand that hypersensitivity reactions are classified into four main types (I, II, III, IV) based on the immune mechanism involved and the timing of the response.
Recall that Type I hypersensitivity reactions are immediate and involve IgE antibodies binding to allergens, leading to rapid release of histamine and other mediators from mast cells and basophils.
Recognize that Type II hypersensitivity involves antibody-mediated cytotoxicity, where IgG or IgM antibodies target cells, leading to their destruction, which is not immediate.
Know that Type III hypersensitivity involves immune complex formation and deposition, causing inflammation, and Type IV is a delayed-type hypersensitivity mediated by T cells, occurring hours to days after exposure.
Since Hannah's reaction is immediate and life-threatening after a wasp sting, identify this as a Type I hypersensitivity reaction.