Starting with one molecule of glucose, glycolysis results in the net production of which of the following sets of energy-containing products? a) 2 NAD+, 2 pyruvate, and 2 ATP. b) 2 NADH, 2 pyruvate, and 2 ATP. c) 4 NADH, 2 pyruvate, and 4 ATP. d) 6 CO2, 2 pyruvate, and 2 ATP.
A
2 NAD+, 2 pyruvate, and 2 ATP.
B
2 NADH, 2 pyruvate, and 2 ATP.
C
4 NADH, 2 pyruvate, and 4 ATP.
D
6 CO2, 2 pyruvate, and 2 ATP.
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1
Understand the process of glycolysis: Glycolysis is the metabolic pathway that converts glucose (C6H12O6) into pyruvate, releasing energy and reducing power in the form of ATP and NADH.
Identify the key outputs of glycolysis: The main products of glycolysis are pyruvate, ATP, and NADH. Specifically, one molecule of glucose is broken down into two molecules of pyruvate.
Calculate the net ATP production: Glycolysis involves substrate-level phosphorylation, resulting in the production of 4 ATP molecules. However, 2 ATP molecules are consumed during the initial steps, leading to a net gain of 2 ATP.
Determine the NADH production: During glycolysis, 2 molecules of NAD+ are reduced to form 2 molecules of NADH. This occurs during the oxidation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate.
Summarize the net products: From one molecule of glucose, glycolysis results in the net production of 2 pyruvate, 2 ATP, and 2 NADH. This matches option b) 2 NADH, 2 pyruvate, and 2 ATP.