Which of the following is the most common pathway taken for a newly synthesized protein to be secreted?
A
Rough ER → Golgi→ Transport vesicle → Nucleus.
B
Golgi → Rough ER → Lysosome → Transport vesicle → Cell membrane.
C
Rough ER → Golgi → Transport vesicle → Cell membrane.
D
Rough ER → Lysosome → Transport vesicle → Cell membrane.
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1
Understand the process of protein synthesis and secretion in eukaryotic cells, which involves several organelles working in a specific sequence.
Recognize that the Rough Endoplasmic Reticulum (Rough ER) is the starting point for the synthesis of proteins destined for secretion. Proteins are synthesized by ribosomes attached to the Rough ER.
After synthesis, proteins are transported from the Rough ER to the Golgi apparatus. The Golgi apparatus modifies, sorts, and packages proteins for secretion.
From the Golgi apparatus, proteins are packaged into transport vesicles. These vesicles are responsible for moving the proteins to their next destination.
Finally, the transport vesicles fuse with the cell membrane, releasing the proteins outside the cell. This is the typical pathway for protein secretion: Rough ER → Golgi → Transport vesicle → Cell membrane.