객관식
How do type IV hypersensitivity reactions differ from type I hypersensitivity reactions?
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- 1. Introduction to Microbiology3h 26m
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27. Immunological Disorders
Type IV Hypersensitivities
객관식
Red, raised, and hardened skin patches in association with tuberculin injections are called indurations. Which cells are responsible for triggering the immune response to the tuberculin which results in indurations?
A
Sensitized B cells.
B
Sensitized T cells.
C
Sensitized plasma cells.
D
Anti-tuberculin antibodies.
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검증된 단계별 안내1
Understand that the tuberculin skin test (Mantoux test) is a type of delayed-type hypersensitivity reaction, which is a cell-mediated immune response rather than an antibody-mediated one.
Recognize that the induration (red, raised, hardened skin patch) results from the activation of immune cells at the site of the tuberculin injection.
Identify that sensitized T cells, specifically memory T helper cells (CD4+), recognize the tuberculin antigen presented by antigen-presenting cells in the skin.
Know that these sensitized T cells release cytokines that recruit and activate macrophages and other immune cells, leading to inflammation and the characteristic induration.
Conclude that sensitized T cells are responsible for triggering the immune response causing the induration, rather than B cells, plasma cells, or antibodies.
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