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Natural Killer Cells definitions
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Natural Killer Cells
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Natural Killer Cells
Innate lymphocytes that eliminate infected host cells by detecting abnormal surface patterns without antigen specificity.
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이 집합의 용어 (14)
하이드의 정의
Natural Killer Cells
Innate lymphocytes that eliminate infected host cells by detecting abnormal surface patterns without antigen specificity.
Innate Immunity
Immediate, non-specific defense mechanism involving cells that do not require prior exposure to pathogens.
Adaptive Immunity
Defense system involving lymphocytes that recognize specific antigens and provide long-lasting protection.
Lymphocytes
White blood cells including NKs, T cells, and B cells, each with distinct roles in immune responses.
Antigen
Molecule or structure on pathogens or infected cells recognized by immune components, triggering a response.
MHC Class I
Surface proteins on healthy cells that present internal peptides; their absence signals abnormality to immune cells.
Apoptosis
Programmed cell death process induced by immune cells to eliminate infected or abnormal host cells.
Perforin
Protein released by NKs that forms pores in target cell membranes, facilitating entry of destructive enzymes.
Proteases
Enzymes in NK cell granules that degrade proteins within target cells, promoting cell death.
Antibody-Dependent Cellular Cytotoxicity
Mechanism where immune cells recognize antibody-coated targets and induce their destruction.
Fc Region
Constant portion of an antibody recognized by NKs, enabling them to bind and kill marked cells.
IgG
Antibody class that binds antigens on infected cells, marking them for immune cell recognition.
Death Packages
Granules released by NKs containing molecules like perforin and proteases to induce apoptosis.
Antigen Presentation
Display of pathogen-derived peptides on cell surfaces, often disrupted by viruses to evade immunity.