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Ch. 22 - Microbial Diseases of the Nervous System
Tortora - Microbiology: An Introduction 14th Edition
Tortora14th EditionMicrobiology: An IntroductionISBN: 9780138200398당신이 사용하는 게 아니라요?교과서 변경
18장, 문제 5

Endotoxin is responsible for symptoms caused by which of the following organisms?
a. N. meningitidis
b. S. pyogenes
c. L. monocytogenes
d. C. tetani
e. C. botulinum

검증된 단계별 안내
1
Understand what an endotoxin is: Endotoxins are lipopolysaccharides (LPS) found in the outer membrane of Gram-negative bacteria. They are released when the bacteria die and cause symptoms such as fever, inflammation, and shock.
Identify which organisms in the list are Gram-negative: Among the options, Neisseria meningitidis (N. meningitidis) is a Gram-negative bacterium, while the others are Gram-positive.
Recall that Gram-positive bacteria do not have an outer membrane and therefore do not produce endotoxins; instead, they may produce exotoxins.
Match the organism that produces endotoxin with the symptoms caused by endotoxin: Since N. meningitidis is Gram-negative, it produces endotoxin responsible for symptoms like meningitis and septic shock.
Conclude that the correct organism responsible for symptoms caused by endotoxin is N. meningitidis.

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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Endotoxins

Endotoxins are toxic components of the outer membrane of Gram-negative bacteria, primarily lipopolysaccharides (LPS). They are released when the bacteria die or multiply, triggering strong immune responses such as fever, inflammation, and septic shock.
추천 영상:
02:46
Endotoxin

Gram-negative vs. Gram-positive Bacteria

Gram-negative bacteria have an outer membrane containing endotoxins, while Gram-positive bacteria lack this outer membrane and instead produce exotoxins. This distinction is crucial for understanding which organisms cause symptoms via endotoxins.
추천 영상:
04:46
Gram-Positive vs. Gram-Negative Cell Walls

Pathogenic Organisms Listed

Among the listed organisms, Neisseria meningitidis is Gram-negative and produces endotoxins. The others (S. pyogenes, L. monocytogenes, C. tetani, C. botulinum) are Gram-positive and cause disease mainly through exotoxins, not endotoxins.
추천 영상:
03:40
Introduction to Pathogenic Toxins